In vitro metabolic profile and drug‐drug interaction assessment of secnidazole, a high‐dose 5‐nitroimidazole antibiotic for the treatment of bacterial vaginosis

A single‐dose oral granule formulation of secnidazole 2 g (SOLOSEC(™)) has been approved in the US as a treatment for bacterial vaginosis. Available data on the likelihood of in vitro drug‐drug and alcohol‐drug interactions are limited. Secnidazole was incubated with cultured human hepatocytes over...

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Detalles Bibliográficos
Autores principales: Pentikis, Helen S., Adetoro, Nikki, Kaufman, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416039/
https://www.ncbi.nlm.nih.gov/pubmed/32776491
http://dx.doi.org/10.1002/prp2.634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416039/
https://www.ncbi.nlm.nih.gov/pubmed/32776491
http://dx.doi.org/10.1002/prp2.634

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