Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of smooth muscle cells (SMCs), but its potential...

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Detalles Bibliográficos
Autores principales: Hou, Xuwei, Li, Zhaohui, Higashi, Yusuke, Delafontaine, Patrice, Sukhanov, Sergiy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416301/
https://www.ncbi.nlm.nih.gov/pubmed/32802505
http://dx.doi.org/10.1155/2020/4939310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416301/
https://www.ncbi.nlm.nih.gov/pubmed/32802505
http://dx.doi.org/10.1155/2020/4939310

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