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Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy
Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of smooth muscle cells (SMCs), but its potential...
Autores principales: | Hou, Xuwei, Li, Zhaohui, Higashi, Yusuke, Delafontaine, Patrice, Sukhanov, Sergiy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416301/ https://www.ncbi.nlm.nih.gov/pubmed/32802505 http://dx.doi.org/10.1155/2020/4939310 |
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