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MZT Proteins Form Multi-Faceted Structural Modules in the γ-Tubulin Ring Complex

Microtubule organization depends on the γ-Tubulin ring complex (γ-TuRC), a ~2.3-MDa nucleation factor comprising an asymmetric assembly of γ-Tubulin and GCP2-GCP6. However, it is currently unclear how the γ-TuRC-associated microproteins MZT1 and MZT2 contribute to the structure and regulation of the...

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Detalles Bibliográficos
Autores principales: Wieczorek, Michal, Huang, Tzu-Lun, Urnavicius, Linas, Hsia, Kuo-Chiang, Kapoor, Tarun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416306/
https://www.ncbi.nlm.nih.gov/pubmed/32610146
http://dx.doi.org/10.1016/j.celrep.2020.107791