Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids

The assessment of potentially sensitive populations is an important application of risk assessment. To address the concern for age-related sensitivity to pyrethroid insecticides, life-stage physiologically based pharmacokinetic (PBPK) modeling supported by in vitro to in vivo extrapolation was condu...

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Detalles Bibliográficos
Autores principales: Mallick, Pankajini, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung, Moreau, Marjory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regulatory Science, Risk Assessment, and Decision Making
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416317/
https://www.ncbi.nlm.nih.gov/pubmed/32421774
http://dx.doi.org/10.1093/toxsci/kfaa070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416317/
https://www.ncbi.nlm.nih.gov/pubmed/32421774
http://dx.doi.org/10.1093/toxsci/kfaa070

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