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The GARDpotency Assay for Potency-Associated Subclassification of Chemical Skin Sensitizers—Rationale, Method Development, and Ring Trial Results of Predictive Performance and Reproducibility

Proactive identification and characterization of hazards attributable to chemicals are central aspects of risk assessments. Current legislations and trends in predictive toxicology advocate a transition from in vivo methods to nonanimal alternatives. For skin sensitization assessment, several OECD v...

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Detalles Bibliográficos
Autores principales: Gradin, Robin, Johansson, Angelica, Forreryd, Andy, Aaltonen, Emil, Jerre, Anders, Larne, Olivia, Mattson, Ulrika, Johansson, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416325/
https://www.ncbi.nlm.nih.gov/pubmed/32421796
http://dx.doi.org/10.1093/toxsci/kfaa068