Synthesis, molecular docking and molecular dynamic simulation studies of 2-chloro-5-[(4-chlorophenyl)sulfamoyl]-N-(alkyl/aryl)-4-nitrobenzamide derivatives as antidiabetic agents

A series of 2-chloro-5-[(4-chlorophenyl)sulfamoyl]-N-(alkyl/aryl)-4-nitrobenzamide derivatives (5a–5v) has been synthesized and confirmed by physicochemical(R(f), melting point) and spectral means (IR, (1)HNMR, (13)CNMR). The results of in vitro antidiabetic study against α-glucosidase indicated tha...

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Detalles Bibliográficos
Autores principales: Thakral, Samridhi, Narang, Rakesh, Kumar, Manoj, Singh, Vikramjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416410/
https://www.ncbi.nlm.nih.gov/pubmed/32789301
http://dx.doi.org/10.1186/s13065-020-00703-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416410/
https://www.ncbi.nlm.nih.gov/pubmed/32789301
http://dx.doi.org/10.1186/s13065-020-00703-4

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