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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
Fructose consumption has risen dramatically in recent decades due to use of sucrose and high fructose corn syrup in beverages and processed foods(1), contributing to rising rates of obesity and non-alcoholic fatty liver disease (NAFLD)(2–4). Fructose intake triggers hepatic de novo lipogenesis (DNL)...
Autores principales: | Zhao, Steven, Jang, Cholsoon, Liu, Joyce, Uehara, Kahealani, Gilbert, Michael, Izzo, Luke, Zeng, Xianfeng, Trefely, Sophie, Fernandez, Sully, Carrer, Alessandro, Miller, Katelyn D., Schug, Zachary T., Snyder, Nathaniel W., Gade, Terence P., Titchenell, Paul M., Rabinowitz, Joshua D., Wellen, Kathryn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416516/ https://www.ncbi.nlm.nih.gov/pubmed/32214246 http://dx.doi.org/10.1038/s41586-020-2101-7 |
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