Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes

The human genome can be segmented into topologically associating domains (TADs), which have been proposed to spatially sequester genes and regulatory elements through chromatin looping. Interactions between TADs have also been suggested, presumably due to variable boundary positions across individua...

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Detalles Bibliográficos
Autores principales: Luppino, Jennifer M., Park, Daniel S., Nguyen, Son C., Lan, Yemin, Xu, Zhuxuan, Yunker, Rebecca, Joyce, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416539/
https://www.ncbi.nlm.nih.gov/pubmed/32572210
http://dx.doi.org/10.1038/s41588-020-0647-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416539/
https://www.ncbi.nlm.nih.gov/pubmed/32572210
http://dx.doi.org/10.1038/s41588-020-0647-9

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