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HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain Injury

Background: Neuronal apoptosis involved in secondary injury following traumatic brain injury (TBI) significantly contributes to the poor outcomes of patients with TBI. The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis of tumor cells. Hypoxia factor...

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Detalles Bibliográficos
Autores principales: Fang, Yuanjian, Lu, Jianan, Wang, Xiaoyu, Wu, Haijian, Mei, Shuhao, Zheng, Jingwei, Xu, Shenbin, Lenahan, Cameron, Chen, Sheng, Zhang, Jianmin, Hong, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416670/
https://www.ncbi.nlm.nih.gov/pubmed/32848609
http://dx.doi.org/10.3389/fncel.2020.00192