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Direct synthesis of amides from nonactivated carboxylic acids using urea as nitrogen source and Mg(NO(3))(2) or imidazole as catalysts

A new method for the direct synthesis of primary and secondary amides from carboxylic acids is described using Mg(NO(3))(2)·6H(2)O or imidazole as a low-cost and readily available catalyst, and urea as a stable, and easy to manipulate nitrogen source. This methodology is particularly useful for the...

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Detalles Bibliográficos
Autores principales: Chhatwal, A. Rosie, Lomax, Helen V., Blacker, A. John, Williams, Jonathan M. J., Marcé, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416778/
https://www.ncbi.nlm.nih.gov/pubmed/32832055
http://dx.doi.org/10.1039/d0sc01317j