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Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis

TMPRSS2 is an important membrane-anchored serine protease involved in human prostate cancer progression and metastasis. A serine protease physiologically often comes together with a cognate inhibitor for execution of proteolytically biologic function; however, TMPRSS2’s cognate inhibitor is still el...

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Detalles Bibliográficos
Autores principales: Ko, Chun-Jung, Hsu, Ting-Wei, Wu, Shang-Ru, Lan, Shao-Wei, Hsiao, Ting-Feng, Lin, Hsin-Ying, Lin, Hsin-Hsien, Tu, Hsin-Fang, Lee, Cheng-Fan, Huang, Cheng-Chung, Chen, Mei-Ju May, Hsiao, Pei-Wen, Huang, Hsiang-Po, Lee, Ming-Shyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416816/
https://www.ncbi.nlm.nih.gov/pubmed/32778768
http://dx.doi.org/10.1038/s41388-020-01413-w