Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

PURPOSE: Electric micro-current has been shown to enhance penetration and transduction of adeno-associated viral (AAV) vectors in mouse retina after intravitreal administration. We termed this: “electric-current vector mobility (ECVM).” The present study considered whether ECVM could augment retinal...

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Detalles Bibliográficos
Autores principales: Song, Hongman, Zeng, Yong, Sardar Pasha, Sheik Pran Babu, Bush, Ronald A., Vijayasarathy, Camasamudram, Qian, Haohua, Wei, Lisa, Wiley, Henry E., Wu, Zhijian, Sieving, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416894/
https://www.ncbi.nlm.nih.gov/pubmed/32844051
http://dx.doi.org/10.1167/tvst.9.7.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416894/
https://www.ncbi.nlm.nih.gov/pubmed/32844051
http://dx.doi.org/10.1167/tvst.9.7.28

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