Concentration-dependent mortality of chloroquine in overdose

Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although generally safe they are potentially lethal in overdose. In-vitro data suggest that high concentrations and thus high doses are needed for COVID-19...

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Detalles Bibliográficos
Autores principales: Watson, James A, Tarning, Joel, Hoglund, Richard M, Baud, Frederic J, Megarbane, Bruno, Clemessy, Jean-Luc, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417172/
https://www.ncbi.nlm.nih.gov/pubmed/32639233
http://dx.doi.org/10.7554/eLife.58631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417172/
https://www.ncbi.nlm.nih.gov/pubmed/32639233
http://dx.doi.org/10.7554/eLife.58631

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