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Concentration-dependent mortality of chloroquine in overdose
Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although generally safe they are potentially lethal in overdose. In-vitro data suggest that high concentrations and thus high doses are needed for COVID-19...
Autores principales: | Watson, James A, Tarning, Joel, Hoglund, Richard M, Baud, Frederic J, Megarbane, Bruno, Clemessy, Jean-Luc, White, Nicholas J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417172/ https://www.ncbi.nlm.nih.gov/pubmed/32639233 http://dx.doi.org/10.7554/eLife.58631 |
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