Characterization of Binding Properties of Individual Functional Sites of Human Complement Factor H

Factor H exists as a 155,000 dalton, extended protein composed of twenty small domains which is flexible enough that it folds back on itself. Factor H regulates complement activation through its interactions with C3b and polyanions. Three binding sites for C3b and multiple polyanion binding sites ha...

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Detalles Bibliográficos
Autores principales: Haque, Aftabul, Cortes, Claudio, Alam, M. Nurul, Sreedhar, Maladi, Ferreira, Viviana P., Pangburn, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417313/
https://www.ncbi.nlm.nih.gov/pubmed/32849614
http://dx.doi.org/10.3389/fimmu.2020.01728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417313/
https://www.ncbi.nlm.nih.gov/pubmed/32849614
http://dx.doi.org/10.3389/fimmu.2020.01728

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