Detection of somatic TP53 mutations and 17p deletions in patients with chronic lymphocytic leukemia: a review of the current methods

Chronic lymphocytic leukemia is the most common hematologic malignancy among adults in Western countries. Several studies show that somatic mutations in the TP53 gene are present in up to 50% of patients with relapsed or refractory chronic lymphocytic leukemia. This study aims to review and compare...

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Detalles Bibliográficos
Autores principales: Chauffaille, Maria de Lourdes L.F., Zalcberg, Ilana, Barreto, Wolney Gois, Bendit, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417461/
https://www.ncbi.nlm.nih.gov/pubmed/32660851
http://dx.doi.org/10.1016/j.htct.2020.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417461/
https://www.ncbi.nlm.nih.gov/pubmed/32660851
http://dx.doi.org/10.1016/j.htct.2020.05.005

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