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Detection of somatic TP53 mutations and 17p deletions in patients with chronic lymphocytic leukemia: a review of the current methods
Chronic lymphocytic leukemia is the most common hematologic malignancy among adults in Western countries. Several studies show that somatic mutations in the TP53 gene are present in up to 50% of patients with relapsed or refractory chronic lymphocytic leukemia. This study aims to review and compare...
Autores principales: | Chauffaille, Maria de Lourdes L.F., Zalcberg, Ilana, Barreto, Wolney Gois, Bendit, Israel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Hematologia e Hemoterapia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417461/ https://www.ncbi.nlm.nih.gov/pubmed/32660851 http://dx.doi.org/10.1016/j.htct.2020.05.005 |
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