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BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62

Molecular chaperones are critical to maintaining intracellular proteostasis and have been shown to have a protective role against alpha-synuclein-mediated toxicity. Co-chaperone proteins regulate the activity of molecular chaperones and connect the chaperone network to protein degradation and cell d...

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Detalles Bibliográficos
Autores principales: Friesen, Erik L., Zhang, Yu Tong, Earnshaw, Rebecca, De Snoo, Mitch L., O’Hara, Darren M., Agapova, Victoria, Chau, Hien, Ngana, Sophie, Chen, Kevin S., Kalia, Lorraine V., Kalia, Suneil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417480/
https://www.ncbi.nlm.nih.gov/pubmed/32850835
http://dx.doi.org/10.3389/fcell.2020.00716