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A Quantitative Analysis of Cellular Lipid Compositions During Acute Proteotoxic ER Stress Reveals Specificity in the Production of Asymmetric Lipids

The unfolded protein response (UPR) is central to endoplasmic reticulum (ER) homeostasis by controlling its size and protein folding capacity. When activated by unfolded proteins in the ER-lumen or aberrant lipid compositions, the UPR adjusts the expression of hundreds of target genes to counteract...

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Detalles Bibliográficos
Autores principales: Reinhard, John, Mattes, Carsten, Väth, Kristina, Radanović, Toni, Surma, Michal A., Klose, Christian, Ernst, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417482/
https://www.ncbi.nlm.nih.gov/pubmed/32850859
http://dx.doi.org/10.3389/fcell.2020.00756