Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapy

Genetic polymorphisms in drug metabolizing enzymes and drug transporters may affect irinotecan toxicity. Although genetic polymorphisms have been shown to influence the irinotecan toxicity, data are limited in Thai population. Thus, the aim of this study was to assess the allele and genotype frequen...

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Detalles Bibliográficos
Autores principales: Atasilp, Chalirmporn, Chansriwong, Phichai, Sirachainan, Ekaphop, Reungwetwattana, Thanyanan, Sirilerttrakul, Suwannee, Chamnanphon, Monpat, Puangpetch, Apichaya, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417535/
https://www.ncbi.nlm.nih.gov/pubmed/32778670
http://dx.doi.org/10.1038/s41598-020-70351-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417535/
https://www.ncbi.nlm.nih.gov/pubmed/32778670
http://dx.doi.org/10.1038/s41598-020-70351-0

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