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Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1
The FUBP1-FUSE complex is an essential component of a transcription molecular machinery that is necessary for tight regulation of expression of many key genes including c-Myc and p21. FUBP1 utilizes its four articulated KH modules, which function cooperatively, for FUSE nucleotide binding. To unders...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417555/ https://www.ncbi.nlm.nih.gov/pubmed/32778776 http://dx.doi.org/10.1038/s41598-020-69832-z |