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An in vivo strategy for knockdown of circular RNAs

Exonic circular RNAs (circRNAs) are highly abundant RNAs generated mostly from exons of protein-coding genes. Assaying the functions of circRNAs is not straightforward as common approaches for circRNA depletion tend to also alter the levels of mRNAs generated from the hosting gene. Here we describe...

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Detalles Bibliográficos
Autores principales: Pamudurti, Nagarjuna Reddy, Patop, Ines Lucia, Krishnamoorthy, Aishwarya, Ashwal-Fluss, Reut, Bartok, Osnat, Kadener, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417560/
https://www.ncbi.nlm.nih.gov/pubmed/32818061
http://dx.doi.org/10.1038/s41421-020-0182-y