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Pharmacokinetics of Pimobendan and Its Metabolite O-Desmethyl-Pimobendan Following Rectal Administration to Healthy Dogs

Objective: This study describes the pharmacokinetics of parent pimobendan (PIM) and its active metabolite, o-desmethyl-pimobendan (ODMP), after oral and rectal administration of pimobendan to healthy dogs. Animals: A total of eight healthy privately owned dogs were used in this study. Procedures: Th...

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Detalles Bibliográficos
Autores principales: Her, Jiwoong, Kuo, Kendon W., Winter, Randolph L., Cruz-Espindola, Crisanta, Bacek, Lenore M., Boothe, Dawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417621/
https://www.ncbi.nlm.nih.gov/pubmed/32851013
http://dx.doi.org/10.3389/fvets.2020.00423