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Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan

MiR-430 is considered an important regulator during embryonic development, but genetic loss-of-function study is still lacking. Here we demonstrated that genetic deletion of the miR-430 cluster resulted in developmental defects in cell movement, germ layer specification, axis patterning and organ pr...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Zhu, Zeyao, Ho, Idy H. T., Shi, Yujian, Li, Jianzhen, Wang, Xia, Chan, Matthew T. V., Cheng, Christopher H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417628/
https://www.ncbi.nlm.nih.gov/pubmed/32849832
http://dx.doi.org/10.3389/fgene.2020.00853