Ranolazine-Mediated Attenuation of Mechanoelectric Feedback in Atrial Myocyte Monolayers

BACKGROUND: Mechanical stretch increases Na(+) inflow into myocytes, related to mechanisms including stretch-activated channels or Na(+)/H(+) exchanger activation, involving Ca(2+) increase that leads to changes in electrophysiological properties favoring arrhythmia induction. Ranolazine is an antia...

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Detalles Bibliográficos
Autores principales: Del-Canto, Irene, Gómez-Cid, Lidia, Hernández-Romero, Ismael, Guillem, María S., Fernández-Santos, María Eugenia, Atienza, Felipe, Such, Luis, Fernández-Avilés, Francisco, Chorro, Francisco J., Climent, Andreu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417656/
https://www.ncbi.nlm.nih.gov/pubmed/32848863
http://dx.doi.org/10.3389/fphys.2020.00922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417656/
https://www.ncbi.nlm.nih.gov/pubmed/32848863
http://dx.doi.org/10.3389/fphys.2020.00922

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