Analysis and Augmentation of the Immunologic Bystander Effects of CAR T Cell Therapy in a Syngeneic Mouse Cancer Model

The therapeutic efficacy of adoptive transfer of T cells transduced with chimeric antigen receptors (CARs) has been limited in the treatment of solid cancers, partly due to tumor antigen heterogeneity. Overcoming lack of universal tumor antigen expression would be achieved if CAR T cells could induc...

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Detalles Bibliográficos
Autores principales: Klampatsa, Astero, Leibowitz, Michael S., Sun, Jing, Liousia, Maria, Arguiri, Evguenia, Albelda, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417672/
https://www.ncbi.nlm.nih.gov/pubmed/32802940
http://dx.doi.org/10.1016/j.omto.2020.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417672/
https://www.ncbi.nlm.nih.gov/pubmed/32802940
http://dx.doi.org/10.1016/j.omto.2020.07.005

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