Overexpression of FNTB and the activation of Ras induce hypertrophy and promote apoptosis and autophagic cell death in cardiomyocytes

Farnesyltransferase (FTase) is an important enzyme that catalyses the modification of protein isoprene downstream of the mevalonate pathway. Previous studies have shown that the tissue of the heart in the suprarenal abdominal aortic coarctation (AAC) group showed overexpression of FTaseβ (FNTB) and...

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Detalles Bibliográficos
Autores principales: Ding, Jie, Chen, Yu X., Chen, Yan, Mou, Yun, Sun, Xiao T., Dai, Dong P., Zhao, Chen Z., Yang, Jian, Hu, Shen J., Guo, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417704/
https://www.ncbi.nlm.nih.gov/pubmed/32579303
http://dx.doi.org/10.1111/jcmm.15533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417704/
https://www.ncbi.nlm.nih.gov/pubmed/32579303
http://dx.doi.org/10.1111/jcmm.15533

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