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Exosomal MiR‐500a‐3p promotes cisplatin resistance and stemness via negatively regulating FBXW7 in gastric cancer

Chemoresistance has been a major challenge in advanced gastric cancer (GC) therapy. Exosomal transfer of oncogenic miRNAs implicates important effects in mediating recipient cell chemoresistance by transmitting active molecules. In this study, we found that microRNA‐500a‐3p was highly expressed in c...

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Detalles Bibliográficos
Autores principales: Lin, Hao, Zhang, Liang, Zhang, Caihua, Liu, Pengpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417713/
https://www.ncbi.nlm.nih.gov/pubmed/32588541
http://dx.doi.org/10.1111/jcmm.15524