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The Role of GnRH Receptor Autoantibodies in Polycystic Ovary Syndrome

OBJECTIVE: Is polycystic ovary syndrome (PCOS) associated with activating autoantibodies (AAb) to the second extracellular loop (ECL2) of gonadotropin-releasing hormone receptor (GnRHR)? DESIGN AND METHODS: We retrospectively screened sera from 40 patients with PCOS and 14 normal controls (NCs) with...

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Detalles Bibliográficos
Autores principales: Kem, David C, Li, Hongliang, Yu, Xichun, Weedin, Elizabeth, Reynolds, Anna C, Forsythe, Elizabeth, Beel, Marci, Fischer, Hayley, Hines, Brendon, Guo, Yankai, Deng, Jielin, Liles, Jonathan T, Nuss, Zachary, Elkosseifi, Myriam, Aston, Christopher E, Burks, Heather R, Craig, LaTasha B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417878/
https://www.ncbi.nlm.nih.gov/pubmed/32803090
http://dx.doi.org/10.1210/jendso/bvaa078