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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...

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Detalles Bibliográficos
Autores principales: Guo, Chaorui, Davies, Michael J., Hawkins, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417949/
https://www.ncbi.nlm.nih.gov/pubmed/32781424
http://dx.doi.org/10.1016/j.redox.2020.101666