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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...
Autores principales: | Guo, Chaorui, Davies, Michael J., Hawkins, Clare L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417949/ https://www.ncbi.nlm.nih.gov/pubmed/32781424 http://dx.doi.org/10.1016/j.redox.2020.101666 |
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