Impaired chondrocyte U3 snoRNA expression in osteoarthritis impacts the chondrocyte protein translation apparatus

Although pathways controlling ribosome activity have been described to regulate chondrocyte homeostasis in osteoarthritis, ribosome biogenesis in osteoarthritis is unexplored. We hypothesized that U3 snoRNA, a non-coding RNA involved in ribosomal RNA maturation, is critical for chondrocyte protein t...

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Detalles Bibliográficos
Autores principales: Ripmeester, Ellen G. J., Caron, Marjolein M. J., van den Akker, G. G. H., Surtel, Don A. M., Cremers, Andy, Balaskas, Panagiotis, Dyer, Philip, Housmans, Bas A. C., Chabronova, Alzbeta, Smagul, Aibek, Fang, Yongxiang, van Rhijn, Lodewijk W., Peffers, Mandy J., Welting, Tim J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417995/
https://www.ncbi.nlm.nih.gov/pubmed/32778764
http://dx.doi.org/10.1038/s41598-020-70453-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417995/
https://www.ncbi.nlm.nih.gov/pubmed/32778764
http://dx.doi.org/10.1038/s41598-020-70453-9

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