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Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica

Fascioliasis is a neglected zoonotic disease that infects humans and ruminant species worldwide. In the absence of vaccines, control of fascioliasis is primarily via anthelminthic treatment with triclabendazole (TCBZ). Parasitic flatworms, including Fasciola hepatica, are active secretors of extrace...

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Detalles Bibliográficos
Autores principales: Davis, Chelsea N., Winters, Ana, Milic, Ivana, Devitt, Andrew, Cookson, Alan, Brophy, Peter M., Morphew, Russell M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418001/
https://www.ncbi.nlm.nih.gov/pubmed/32778698
http://dx.doi.org/10.1038/s41598-020-69970-4