Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis

Osteoarthritis (OA) affects nearly 10% of the population of the United States and other industrialized countries and, at present, short of surgical joint replacement, there is no therapy available that can reverse the progression of the disease. Adenosine, acting at its A2A receptor (A2AR), is a cri...

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Detalles Bibliográficos
Autores principales: Corciulo, Carmen, Castro, Cristina M., Coughlin, Thomas, Jacob, Samson, Li, Zhu, Fenyö, David, Rifkin, Daniel B., Kennedy, Oran D., Cronstein, Bruce Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418027/
https://www.ncbi.nlm.nih.gov/pubmed/32778777
http://dx.doi.org/10.1038/s41598-020-68302-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418027/
https://www.ncbi.nlm.nih.gov/pubmed/32778777
http://dx.doi.org/10.1038/s41598-020-68302-w

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