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Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis
Osteoarthritis (OA) affects nearly 10% of the population of the United States and other industrialized countries and, at present, short of surgical joint replacement, there is no therapy available that can reverse the progression of the disease. Adenosine, acting at its A2A receptor (A2AR), is a cri...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418027/ https://www.ncbi.nlm.nih.gov/pubmed/32778777 http://dx.doi.org/10.1038/s41598-020-68302-w |