Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents

We report that phenacyl azides are key compounds for a regiodivergent synthesis of valuable, functionalized imidazole (32–98% yield) and pyrimidine derivatives (45–88% yield), with a broad substrate scope, when using deep eutectic solvents [choline chloride (ChCl)/glycerol (1:2 mol/mol) and ChCl/ure...

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Detalles Bibliográficos
Autores principales: Vitale, Paola, Cicco, Luciana, Cellamare, Ilaria, Perna, Filippo M, Salomone, Antonio, Capriati, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418094/
https://www.ncbi.nlm.nih.gov/pubmed/32802208
http://dx.doi.org/10.3762/bjoc.16.158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418094/
https://www.ncbi.nlm.nih.gov/pubmed/32802208
http://dx.doi.org/10.3762/bjoc.16.158

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