Diastereoselective Synthesis of β-Lactams by Ligand-Controlled Stereodivergent Intramolecular Tsuji–Trost Allylation

[Image: see text] The diastereoselective synthesis of highly substituted β-lactams by intramolecular Tsuji–Trost allylation is reported. Judicious selection of the ligand on palladium allows selective access to either the trans isomer (in generally good to excellent yield with very high diastereomer...

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Detalles Bibliográficos
Autores principales: Faltracco, Matteo, Sukowski, Verena, van Druenen, Max, Hamlin, Trevor A., Bickelhaupt, F. Matthias, Ruijter, Eelco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418107/
https://www.ncbi.nlm.nih.gov/pubmed/32584576
http://dx.doi.org/10.1021/acs.joc.0c00575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418107/
https://www.ncbi.nlm.nih.gov/pubmed/32584576
http://dx.doi.org/10.1021/acs.joc.0c00575

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