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Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter

Cell proliferation changes concomitantly with fate transitions during reprogramming, differentiation, regeneration, and oncogenesis. Methods to resolve cell cycle length heterogeneity in real time are currently lacking. Here, we describe a genetically encoded fluorescent reporter that captures live-...

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Detalles Bibliográficos
Autores principales: Eastman, Anna E., Chen, Xinyue, Hu, Xiao, Hartman, Amaleah A., Morales, Aria M. Pearlman, Yang, Cindy, Lu, Jun, Kueh, Hao Yuan, Guo, Shangqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418154/
https://www.ncbi.nlm.nih.gov/pubmed/32579930
http://dx.doi.org/10.1016/j.celrep.2020.107804