Ethosome-Derived Invasomes as a Potential Transdermal Delivery System for Vardenafil Hydrochloride: Development, Optimization and Application of Physiologically Based Pharmacokinetic Modeling in Adults and Geriatrics

AIM: The aim of the current work was to develop vardenafil hydrochloride (VRD)-loaded ethosome-derived invasomes as a possible transdermal system which could be used for patients suffering from pulmonary arterial hypertension. METHODS: VRD-loaded ethosomes were developed at three concentrations of p...

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Detalles Bibliográficos
Autores principales: Ammar, Hussein O, Tadros, Mina Ibrahim, Salama, Nahla M, Ghoneim, Amira Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418156/
https://www.ncbi.nlm.nih.gov/pubmed/32821096
http://dx.doi.org/10.2147/IJN.S261764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418156/
https://www.ncbi.nlm.nih.gov/pubmed/32821096
http://dx.doi.org/10.2147/IJN.S261764

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