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FGL1 regulates acquired resistance to Gefitinib by inhibiting apoptosis in non-small cell lung cancer

BACKGROUND: This study investigated the role of fibrinogen-like protein 1 (FGL1) in regulating gefitinib resistance of PC9/GR non-small cell lung cancer (NSCLC). METHODS: The effect of different concentrations of gefitinib on cell proliferation were evaluated using the CCK-8 assay. FGL1 expression i...

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Detalles Bibliográficos
Autores principales: Sun, Cuilan, Gao, Weiwei, Liu, Jiatao, Cheng, Hao, Hao, Jiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418324/
https://www.ncbi.nlm.nih.gov/pubmed/32778129
http://dx.doi.org/10.1186/s12931-020-01477-y