Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells

BACKGROUND: The three-dimensional organization of the genome in the nucleus plays an integral role in many biological processes, including gene expression. The genome is folded into DNA loops that bring together distal regulatory elements and genes. Cohesin, a ring-shaped protein complex, is a major...

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Detalles Bibliográficos
Autores principales: Arruda, Nicole L., Carico, Zachary M., Justice, Megan, Liu, Ying Frances, Zhou, Junjie, Stefan, Holden C., Dowen, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418333/
https://www.ncbi.nlm.nih.gov/pubmed/32778134
http://dx.doi.org/10.1186/s13072-020-00353-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418333/
https://www.ncbi.nlm.nih.gov/pubmed/32778134
http://dx.doi.org/10.1186/s13072-020-00353-9

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