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The reduction in CD8(+)PD-1(+) T cells in liver histological tissue is related to Pegylated IFN-α therapy outcomes in chronic hepatitis B patients

BACKGROUND: Antiviral therapy is recommended for patients with immune-active chronic hepatitis B (CHB) to decrease the risk of liver-related complications. However, the outcomes of the pegylated IFN-α (PEG-IFN-α) therapy vary among CHB patients. We aimed to identify factors that can influence the ou...

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Detalles Bibliográficos
Autores principales: Liu, Ruyu, Chen, Yanhui, Guo, Jiang, Li, Minghui, Lu, Yao, Zhang, Lu, Shen, Ge, Wu, Shuling, Chang, Min, Hu, Leiping, Hao, Hongxiao, Zhang, Henghui, Xie, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418392/
https://www.ncbi.nlm.nih.gov/pubmed/32778058
http://dx.doi.org/10.1186/s12879-020-05320-z