Cargando…

Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

The dopamine (DA) system has a profound impact on reward-motivated behavior and is critically involved in neurodevelopmental disorders, such as autism spectrum disorder (ASD). Although DA defects are found in autistic patients, it is not well defined how the DA pathways are altered in ASD and whethe...

Descripción completa

Detalles Bibliográficos
Autores principales: Chao, Owen Y., Pathak, Salil S., Zhang, Hao, Dunaway, Nathan, Li, Jay-Shake, Mattern, Claudia, Nikolaus, Susanne, Huston, Joseph P., Yang, Yi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418402/
https://www.ncbi.nlm.nih.gov/pubmed/32778145
http://dx.doi.org/10.1186/s13041-020-00649-7