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Melatonin Plays a Protective Role by Regulating miR-26a-5p-NRSF and JAK2-STAT3 Pathway to Improve Autophagy, Inflammation and Oxidative Stress of Cerebral Ischemia-Reperfusion Injury

BACKGROUND: Melatonin (MT) has potential protective effect on cerebral ischemia-reperfusion injury (CIRI), but its underlying regulatory mechanism has not been identified. PURPOSE: This study aimed to explore the role of miR-26a-5p-neuron-restrictive silencing factor (NRSF/REST), Janus kinase-2 (JAK...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Zang, Li-E, Cui, Jing-Wen, Zhang, Ming-Yuan, Ma, Xue, Wei, Lin-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418459/
https://www.ncbi.nlm.nih.gov/pubmed/32821085
http://dx.doi.org/10.2147/DDDT.S262121