Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels

Erastin is a small molecular compound that induces ferroptosis by binding to voltage-dependent anion-selective channel protein (VDAC)2, VDAC3 and solute carrier family 7 member 5 inhibiting the cystine/glutamate antiporter. However, to the best of our knowledge, the mechanism of erastin-induced brea...

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Detalles Bibliográficos
Autores principales: Li, Mengxin, Wang, Xuanzhong, Lu, Shan, He, Chuan, Wang, Chongcheng, Wang, Lei, Wang, Xinyu, Ge, Pengfei, Song, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418505/
https://www.ncbi.nlm.nih.gov/pubmed/32793311
http://dx.doi.org/10.3892/ol.2020.11918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418505/
https://www.ncbi.nlm.nih.gov/pubmed/32793311
http://dx.doi.org/10.3892/ol.2020.11918

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