Cargando…

Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels

Erastin is a small molecular compound that induces ferroptosis by binding to voltage-dependent anion-selective channel protein (VDAC)2, VDAC3 and solute carrier family 7 member 5 inhibiting the cystine/glutamate antiporter. However, to the best of our knowledge, the mechanism of erastin-induced brea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Mengxin, Wang, Xuanzhong, Lu, Shan, He, Chuan, Wang, Chongcheng, Wang, Lei, Wang, Xinyu, Ge, Pengfei, Song, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418505/ https://www.ncbi.nlm.nih.gov/pubmed/32793311 http://dx.doi.org/10.3892/ol.2020.11918

Ejemplares similares

Autophagy activated by silibinin contributes to glioma cell death via induction of oxidative stress-mediated BNIP3-dependent nuclear translocation of AIF
por: Wang, Chongcheng, et al.
Publicado: (2020)

Synergistic Effect of Erastin Combined with Nutlin-3 on Vestibular Schwannoma Cells as p53 Modulates Erastin-Induced Ferroptosis Response
por: He, Weiwei, et al.
Publicado: (2022)

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
por: Santoni, M, et al.
Publicado: (2013)

Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells: Role of PDI in ferroptosis
por: Hou, Ming-Jie, et al.
Publicado: (2023)

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
por: Kwon, Min-Young, et al.
Publicado: (2015)

Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
por: Battaglia, Anna Martina, et al.
Publicado: (2022)

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis
por: Yan, Renhong, et al.
Publicado: (2022)

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
por: Zhao, Yuechen, et al.
Publicado: (2020)

Monitoring and Regulating Intracellular GPX4 mRNA Using Gold Nanoflare Probes and Enhancing Erastin-Induced Ferroptosis
por: Liu, Xiaoyan, et al.
Publicado: (2022)

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc(–)
por: Wang, Liyuan, et al.
Publicado: (2019)

Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis
por: Chen, Cong, et al.
Publicado: (2022)

Erastin Disrupts Mitochondrial Permeability Transition Pore (mPTP) and Induces Apoptotic Death of Colorectal Cancer Cells
por: Huo, Haizhong, et al.
Publicado: (2016)

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
por: Wang, Yue-Qi, et al.
Publicado: (2016)

Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field
por: Du, Shaohua, et al.
Publicado: (2016)

How erastin assassinates cells by ferroptosis revealed
por: Gan, Boyi
Publicado: (2022)

Maltol inhibits oxygen glucose deprivation‑induced chromatinolysis in SH‑SY5Y cells by maintaining pyruvate level
por: Zhang, Shuyan, et al.
Publicado: (2023)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Erastin inhibits porcine epidemic diarrhea virus replication in Vero cells
por: Zhang, Hongliang, et al.
Publicado: (2023)

Melatonin and erastin emerge synergistic anti-tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS
por: Wang, Leilei, et al.
Publicado: (2023)

Arginine Expedites Erastin-Induced Ferroptosis through Fumarate
por: Guo, Xinxin, et al.
Publicado: (2023)

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death
por: Dächert, Jasmin, et al.
Publicado: (2016)

Cardiac arrest triggers hippocampal neuronal death through autophagic and apoptotic pathways
por: Cui, Derong, et al.
Publicado: (2016)

Triggering autophagic cell death with a di-manganese(II) developmental therapeutic
por: Slator, Creina, et al.
Publicado: (2017)

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons
por: Zhang, Yan, et al.
Publicado: (2020)

Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer
por: Zhou, Hai-Hong, et al.
Publicado: (2019)

Iron-Dependent Autophagic Cell Death Induced by Radiation in MDA-MB-231 Breast Cancer Cells
por: Ma, Shumei, et al.
Publicado: (2021)

Plasma‐activated medium triggers immunomodulation and autophagic activity for periodontal regeneration
por: Wang, Shengfang, et al.
Publicado: (2023)

Autophagic Cell Death and Cancer
por: Shimizu, Shigeomi, et al.
Publicado: (2014)

ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron
por: Lu, Shan, et al.
Publicado: (2021)

Blue LED causes autophagic cell death in human osteosarcoma by increasing ROS generation and dephosphorylating EGFR
por: He, Mingyu, et al.
Publicado: (2021)

Cyclophilin A contributes to shikonin-induced glioma cell necroptosis and promotion of chromatinolysis
por: Wang, Xinyu, et al.
Publicado: (2022)

NMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion
por: Wang, Guangyun, et al.
Publicado: (2020)

Chloride intracellular channel gene knockdown induces insect cell lines death and level increases of intracellular calcium ions
por: Song, Jiqiang, et al.
Publicado: (2023)

Targeted exosome‐encapsulated erastin induced ferroptosis in triple negative breast cancer cells
por: Yu, Mengyu, et al.
Publicado: (2019)

Traditional Uyghur medicine Quercus infectoria galls water extract triggers apoptosis and autophagic cell death in colorectal cancer cells
por: Zhang, Hui, et al.
Publicado: (2020)

Curcumin and (−)- Epigallocatechin-3-Gallate Protect Murine MIN6 Pancreatic Beta-Cells against Iron Toxicity and Erastin-Induced Ferroptosis
por: Kose, Tugba, et al.
Publicado: (2019)

Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
por: Mansilla Pareja, Maria Eugenia, et al.
Publicado: (2013)

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils
por: Prajsnar, Tomasz K., et al.
Publicado: (2020)

Cold PSM, but not TRAIL, triggers autophagic cell death: A therapeutic advantage of PSM over TRAIL
por: Ito, Tomohisa, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1uek470frkkgka612j82ajf5a8