Vitamin C is a source of oxoaldehyde and glycative stress in age‐related cataract and neurodegenerative diseases

Oxoaldehyde stress has recently emerged as a major source of tissue damage in aging and age‐related diseases. The prevailing mechanism involves methylglyoxal production during glycolysis and modification of arginine residues through the formation of methylglyoxal hydroimidazolones (MG‐H1). We now te...

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Detalles Bibliográficos
Autores principales: Fan, Xingjun, Sell, David R., Hao, Caili, Liu, Sabrina, Wang, Benlian, Wesson, Daniel W., Siedlak, Sandra, Zhu, Xiongwei, Kavanagh, Terrance J., Harrison, Fiona E., Monnier, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418511/
https://www.ncbi.nlm.nih.gov/pubmed/32567221
http://dx.doi.org/10.1111/acel.13176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418511/
https://www.ncbi.nlm.nih.gov/pubmed/32567221
http://dx.doi.org/10.1111/acel.13176

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