Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16

The serine/threonine kinase CK2 modulates the activity of more than 300 proteins and thus plays a crucial role in various physiological and pathophysiological processes including neurodegenerative disorders of the central nervous system and cancer. The enzymatic activity of CK2 is controlled by the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kröger, Lukas, Daniliuc, Constantin G., Ensan, Deeba, Borgert, Sebastian, Nienberg, Christian, Lauwers, Miriam, Steinkrüger, Michaela, Jose, Joachim, Pietsch, Markus, Wünsch, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418559/
https://www.ncbi.nlm.nih.gov/pubmed/32168422
http://dx.doi.org/10.1002/cmdc.202000040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418559/
https://www.ncbi.nlm.nih.gov/pubmed/32168422
http://dx.doi.org/10.1002/cmdc.202000040

Ejemplares similares