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Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

Vaccine efforts against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the current COVID-19 pandemic are focused on SARS-CoV-2 spike glycoprotein, the primary target for neutralizing antibodies. Here, we performed cryo-EM and site-specific glycan analysis of one of...

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Detalles Bibliográficos
Autores principales: Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418715/
https://www.ncbi.nlm.nih.gov/pubmed/32793901
http://dx.doi.org/10.1101/2020.08.06.234674